Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | DRD5 | P21918 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.41 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.41 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.41 |
| ▸ | BRSK1 | Q8TDC3 | 1/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.41 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.41 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8816877 | 0.95 | HRH1 (0.43) | ACHEDRD2DRD1DRD4DRD5 | |
| SCHEMBL8818593 | 0.90 | ACHE (0.46) | ACHELTA4HPARP1TUBB4ATUBB | |
| SCHEMBL8817574 | 0.89 | MAPT (0.42) | PARP1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL8817590 | 0.89 | MAPT (0.42) | PARP1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL8818631 | 0.88 | ACHE (0.42) | ACHEDRD2PARP1DYRK3MAP4K4 | |
| SCHEMBL8818551 | 0.87 | MAPT (0.47) | PARP1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL8817619 | 0.86 | ACHE (0.40) | ACHEDRD2PARP1DYRK3MAP4K4 | |
| SCHEMBL8078747 | 0.84 | LTA4H (0.47) | ACHEDRD2DRD1DRD4DRD5 | |
| SCHEMBL8079418 | 0.84 | PARP1 (0.41) | ACHEPARP1DYRK3MAP4K4PIM1 | |
| SCHEMBL8814982 | 0.83 | LTA4H (0.46) | ACHEDRD2LTA4HMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997031635-A1 | METHODS OF TREATING OR PREVENTING SLEEP APNEA | ELI LILLY AND COMPANY (US) | 1997-09-04 | — | — | WO | claimed |
| WO-1997031635-A1 | METHODS OF TREATING OR PREVENTING SLEEP APNEA | ELI LILLY AND COMPANY (US) | 1997-09-04 | — | — | WO | disclosed |