Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 7/20 | 0.41 |
| ▸ | TUBB | P07437 | 7/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 7/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 7/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 7/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 7/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 7/20 | 0.41 |
| ▸ | TUBB2A | Q13885 | 7/20 | 0.41 |
| ▸ | TUBB8 | Q3ZCM7 | 7/20 | 0.41 |
| ▸ | TUBA3E | Q6PEY2 | 7/20 | 0.41 |
| ▸ | TUBA1A | Q71U36 | 7/20 | 0.41 |
| ▸ | TUBA1C | Q9BQE3 | 7/20 | 0.41 |
| ▸ | TUBB6 | Q9BUF5 | 7/20 | 0.41 |
| ▸ | TUBB2B | Q9BVA1 | 7/20 | 0.41 |
| ▸ | TUBB1 | Q9H4B7 | 7/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8817574 | 0.96 | MAPT (0.42) | MAPTPARP1TP53TUBB4ATUBB | |
| SCHEMBL8816877 | 0.90 | HRH1 (0.43) | MAPTPARP1TP53TUBB4ATUBB | |
| SCHEMBL8818551 | 0.89 | MAPT (0.47) | MAPTPARP1TP53TUBB4ATUBB | |
| SCHEMBL8816611 | 0.89 | ACHE (0.44) | MAPTPARP1TP53TUBB4ATUBB | |
| SCHEMBL8818593 | 0.86 | ACHE (0.46) | MAPTPARP1TP53TUBB4ATUBB | |
| SCHEMBL8071362 | 0.86 | DHODH (0.47) | PARP1DHODH | |
| SCHEMBL8078747 | 0.86 | LTA4H (0.47) | PARP1DHODH | |
| SCHEMBL8814982 | 0.85 | LTA4H (0.46) | MAPTKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL8079505 | 0.85 | ACHE (0.46) | PARP1DHODH | |
| SCHEMBL8079672 | 0.85 | ACHE (0.46) | PARP1DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997031635-A1 | METHODS OF TREATING OR PREVENTING SLEEP APNEA | ELI LILLY AND COMPANY (US) | 1997-09-04 | — | — | WO | disclosed |