Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31504176 | 0.82 | DGKA (0.46) | DGKAHTR2CCYP1A2ADRA2AADRA1A | |
| SCHEMBL15854765 | 0.80 | HTR2C (0.47) | DGKAHTR2CCYP1A2ADRA2AADRA1A | |
| SCHEMBL27532241 | 0.79 | DGKA (0.61) | DGKAHTR2CCYP1A2DNM1MAPT | |
| SCHEMBL11257090 | 0.79 | DGKA (0.61) | DGKAHTR2CDNM1MAPTPRSS1 | |
| SCHEMBL1031828 | 0.79 | — | — | |
| SCHEMBL26130094 | 0.77 | DGKA (0.57) | DGKAHTR2CCYP1A2ADRA2AADRA1A | |
| SCHEMBL28707423 | 0.76 | DGKA (0.68) | DGKAHTR2CDNM1MAPTPRSS1 | |
| SCHEMBL27847362 | 0.75 | DGKA (0.48) | DGKAHTR2CCYP1A2ADRA2AADRA1A | |
| SCHEMBL3478460 | 0.74 | NAAA (0.59) | DGKAHTR2CCYP1A2ADRA2AADRA1A | |
| SCHEMBL316947 | 0.73 | DGKA (0.64) | DGKAHTR2CDNM1MAPTPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997030060-A1 | SUBSTITUTED AROMATIC PHOSPHONIC ACID DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 1997-08-21 | — | — | WO | disclosed |