SCHEMBL8816807

SCHEMBL8816807

C[C](C)COC(=O)C(C)(C)C

nearest known ligand 0.42

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PRKCA P17252 1/20 0.42
BTN3A1 O00481 6/20 0.39
GAA P10253 2/20 0.36
POLB P06746 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
ALDH1A1 P00352 2/20 0.34
ELANE P08246 3/20 0.33
CYP4F2 P78329 1/20 0.32
CYP4A11 Q02928 1/20 0.32
LMNA P02545 1/20 0.32
HSD17B10 Q99714 1/20 0.32
ENO1 P06733 1/20 0.31
MAPK1 P28482 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3517297 0.84 PRKCA (0.42) PRKCABTN3A1GAAPOLBNPSR1
SCHEMBL15928824 0.80 PRKCA (0.39) PRKCABTN3A1GAAPOLBNPSR1
SCHEMBL9714746 0.80 PRKCA (0.39) PRKCABTN3A1GAAPOLBNPSR1
SCHEMBL7089654 0.79 PRKCA (0.42) PRKCABTN3A1GAAPOLBNPSR1
SCHEMBL9866275 0.79 PRKCA (0.42) PRKCABTN3A1GAAPOLBNPSR1
SCHEMBL13647509 0.79 MAPK1 (0.47) PRKCABTN3A1GAAPOLBNPSR1
SCHEMBL15976179 0.78 BTN3A1 (0.39) PRKCABTN3A1GAAPOLBNPSR1
SCHEMBL9871939 0.77 PRKCA (0.41) PRKCABTN3A1GAAPOLBNPSR1
SCHEMBL7222887 0.77 PRKCA (0.41) PRKCABTN3A1GAAPOLBNPSR1
SCHEMBL6205519 0.77 PRKCA (0.41) PRKCABTN3A1GAAPOLBNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1997041128-A1 3-PYRAZOLIOMETHYLCEPHEM COMPOUNDS AS ANTIMICROBIAL AGENTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1997-11-06 WO disclosed
EP-0307804-B1 Cephem compound and a process for preparation thereof FUJISAWA PHARMACEUTICAL CO (JP) 1993-11-18 EP disclosed
US-5187160-A CEPHEM COMPOUND FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1993-02-16 US disclosed
EP-0386689-A1 New cephem compound and a process for preparation thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1990-09-12 EP disclosed
US-4952578-A Cephem compound and a process for preparation thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1990-08-28 US disclosed
EP-0307804-A2 Cephem compound and a process for preparation thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1989-03-22 EP disclosed