Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | BTN3A1 | O00481 | 5/20 | 0.33 |
| ▸ | ELANE | P08246 | 3/20 | 0.32 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.31 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28019636 | 0.79 | PRKCA (0.43) | PRKCAPOLBGAANPSR1BTN3A1 | |
| SCHEMBL9714746 | 0.78 | PRKCA (0.39) | PRKCAPOLBGAANPSR1BTN3A1 | |
| SCHEMBL7089654 | 0.77 | PRKCA (0.42) | PRKCAPOLBGAANPSR1BTN3A1 | |
| SCHEMBL13647509 | 0.77 | MAPK1 (0.47) | PRKCAPOLBGAANPSR1BTN3A1 | |
| SCHEMBL3517297 | 0.77 | PRKCA (0.42) | PRKCAPOLBGAANPSR1BTN3A1 | |
| SCHEMBL8816807 | 0.77 | PRKCA (0.42) | PRKCAPOLBGAANPSR1BTN3A1 | |
| SCHEMBL9866275 | 0.77 | PRKCA (0.42) | PRKCAPOLBGAANPSR1BTN3A1 | |
| SCHEMBL15976179 | 0.76 | BTN3A1 (0.39) | PRKCAPOLBGAANPSR1BTN3A1 | |
| SCHEMBL7222887 | 0.75 | PRKCA (0.41) | PRKCAPOLBGAANPSR1BTN3A1 | |
| SCHEMBL6205519 | 0.75 | PRKCA (0.41) | PRKCAPOLBGAANPSR1BTN3A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4181733-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1980-01-01 | — | — | US | claimed |
| US-5021566-A | Carbapenicillins; preservatives; antiseptics; grampositive and gram negative bacteria | MERCK & CO. INC. (US) | 1991-06-04 | — | — | US | disclosed |
| US-4957912-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1990-09-18 | — | — | US | disclosed |
| US-4707547-A | AMINATION TO FORM ANTIBIOTIC | MERCK & CO., INC. (US) | 1987-11-17 | — | — | US | disclosed |
| US-4530841-A | Antibiotic containing hetero ring | MERCK & CO., INC. (US) | 1985-07-23 | — | — | US | disclosed |
| EP-0134301-A1 | 6-(1'-Hydroxyethyl)-3-substituted amino-1-azabicyclo(3.2.0)-hept-2-en-7-one-2-carboxylic acid | MERCK & CO. INC. (US) | 1985-03-20 | — | — | EP | disclosed |
| US-4424230-A | CARBAPENICILLIN ANTIBIOTICS | MERCK & CO., INC. (US) | 1984-01-03 | — | — | US | disclosed |
| US-4397861-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1983-08-09 | — | — | US | disclosed |
| US-4369187-A | AMINO ACID DERIVATIVE ANTIBIOTICS | MERCK & CO., INC. (US) | 1983-01-18 | — | — | US | disclosed |
| US-4357342-A | 1-Azabicyclo[3.2.0]heptan-3,7-dione-2-carboxylic acid | MERCK & CO., INC. (US) | 1982-11-02 | — | — | US | disclosed |
| US-4196211-A | ANTIBIOTIC | MERCK & CO., INC. (US) | 1980-04-01 | — | — | US | disclosed |
| US-4194047-A | Substituted N-methylene derivatives of thienamycin | MERCK & CO., INC. (US) | 1980-03-18 | — | — | US | disclosed |
| US-4181733-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1980-01-01 | — | — | US | disclosed |
| US-4172144-A | Schiff's base derivatives of thienamycin | MERCK & CO., INC. (US) | 1979-10-23 | — | — | US | disclosed |
| US-4150145-A | ANTIBIOTIC, BACTERICIDES | MERCK & CO., INC. (US) | 1979-04-17 | — | — | US | disclosed |
| EP-0001264-A1 | Substituted N-methylene derivatives of thienamycin sulfoxide and sulfone and their preparation | MERCK & CO. INC. (US) | 1979-04-04 | — | — | EP | disclosed |
| EP-0001265-A1 | O-, N- and carboxyl derivatives of thienamycin sulfoxide and sulfone, their preparation and pharmaceuticals containing said compounds | MERCK & CO. INC. (US) | 1979-04-04 | — | — | EP | disclosed |
| US-4078068-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1978-03-07 | — | — | US | disclosed |
| US-4078067-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1978-03-07 | — | — | US | disclosed |
| US-4076826-A | ANTIBIOTIC | MERCK & CO., INC. (US) | 1978-02-28 | — | — | US | disclosed |