Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 4/20 | 0.32 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.31 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | BTN3A1 | O00481 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8553384 | 0.81 | PRKCA (0.38) | PRKCAPOLBGAANPSR1ELANE | |
| SCHEMBL28019636 | 0.79 | PRKCA (0.43) | PRKCAPOLBGAANPSR1ELANE | |
| SCHEMBL9866275 | 0.77 | PRKCA (0.42) | PRKCAPOLBGAANPSR1ELANE | |
| SCHEMBL3517297 | 0.77 | PRKCA (0.42) | PRKCAPOLBGAANPSR1ELANE | |
| SCHEMBL7089654 | 0.77 | PRKCA (0.42) | PRKCAPOLBGAANPSR1ELANE | |
| SCHEMBL13647509 | 0.77 | MAPK1 (0.47) | PRKCAPOLBGAANPSR1ELANE | |
| SCHEMBL8816807 | 0.77 | PRKCA (0.42) | PRKCAPOLBGAANPSR1ELANE | |
| SCHEMBL6205519 | 0.75 | PRKCA (0.41) | PRKCAPOLBGAANPSR1ELANE | |
| SCHEMBL9871939 | 0.75 | PRKCA (0.41) | PRKCAPOLBGAANPSR1ELANE | |
| SCHEMBL300 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6552226-B1 | Rapid; low temperature; one pot synthesis; reduced catalytic quantities of such as lewis acid and tertiary amine; entiomerically pure products | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2003-04-22 | — | — | US | disclosed |