Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 6/20 | 0.52 |
| ▸ | DHODH | Q02127 | 2/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.47 |
| ▸ | PARP1 | P09874 | 2/20 | 0.47 |
| ▸ | LTA4H | P09960 | 3/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.44 |
| ▸ | YES1 | P07947 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.44 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8816596 | 0.83 | ACHE (0.48) | ACHEDHODHADORA2AADORA1PARP1 | |
| SCHEMBL8079568 | 0.81 | ACHE (0.46) | ACHEDHODHADORA2AADORA1PARP1 | |
| SCHEMBL8816735 | 0.79 | TP53 (0.49) | DHODHPARP1 | |
| SCHEMBL8816605 | 0.78 | ACHE (0.52) | ACHEDHODHADORA2AADORA1PARP1 | |
| SCHEMBL8817571 | 0.78 | ACHE (0.52) | ACHEDHODHADORA2AADORA1PARP1 | |
| SCHEMBL8814893 | 0.76 | ACHE (0.51) | ACHEDHODHADORA2AADORA1PARP1 | |
| SCHEMBL8817544 | 0.72 | MGAM (0.50) | DHODH | |
| SCHEMBL8079505 | 0.71 | ACHE (0.46) | ACHEDHODHADORA2APARP1LTA4H | |
| SCHEMBL8079672 | 0.71 | ACHE (0.46) | ACHEDHODHADORA2APARP1LTA4H | |
| SCHEMBL21018067 | 0.70 | ACHE (0.81) | ACHEDHODHPARP1LTA4HTBK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997031635-A1 | METHODS OF TREATING OR PREVENTING SLEEP APNEA | ELI LILLY AND COMPANY (US) | 1997-09-04 | — | — | WO | disclosed |