Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 5/20 | 0.52 |
| ▸ | DHODH | Q02127 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 5/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
| ▸ | HRH1 | P35367 | 3/20 | 0.44 |
| ▸ | DRD1 | P21728 | 2/20 | 0.44 |
| ▸ | DRD4 | P21917 | 2/20 | 0.44 |
| ▸ | DRD5 | P21918 | 2/20 | 0.44 |
| ▸ | DRD3 | P35462 | 2/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8816605 | 1.00 | ACHE (0.52) | ACHEDHODHCYP1A2CYP2D6GRIN2B | |
| SCHEMBL8814893 | 0.99 | ACHE (0.51) | ACHEDHODHCYP1A2CYP2D6GRIN2B | |
| SCHEMBL8818817 | 0.91 | ACHE (0.53) | ACHEDHODHLTA4HADORA2AADORA1 | |
| SCHEMBL8079505 | 0.84 | ACHE (0.46) | ACHEDHODHLTA4HADORA2APARP1 | |
| SCHEMBL8079672 | 0.84 | ACHE (0.46) | ACHEDHODHLTA4HADORA2APARP1 | |
| SCHEMBL8891323 | 0.84 | DHODH (0.42) | DHODHKDM4EL3MBTL1 | |
| SCHEMBL8818920 | 0.84 | DHODH (0.42) | DHODHKDM4EL3MBTL1 | |
| SCHEMBL8078747 | 0.83 | LTA4H (0.47) | ACHEDHODHLTA4HPARP1HRH1 | |
| SCHEMBL8818678 | 0.83 | DYRK3 (0.48) | ACHEDHODHLTA4HADORA2AADORA1 | |
| SCHEMBL8819001 | 0.82 | CHEK2 (0.44) | ACHEDHODHLTA4HHRH1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997031635-A1 | METHODS OF TREATING OR PREVENTING SLEEP APNEA | ELI LILLY AND COMPANY (US) | 1997-09-04 | — | — | WO | disclosed |