Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 7/20 | 0.50 |
| ▸ | GAA | P10253 | 7/20 | 0.50 |
| ▸ | SI | P14410 | 7/20 | 0.50 |
| ▸ | MGAM2 | Q2M2H8 | 7/20 | 0.50 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.48 |
| ▸ | DHODH | Q02127 | 7/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8818550 | 0.85 | MGAM (0.51) | MGAMGAASIMGAM2RPS6KA3 | |
| SCHEMBL8816735 | 0.82 | TP53 (0.49) | MGAMGAASIMGAM2RPS6KA3 | |
| SCHEMBL8814846 | 0.73 | MGAM (0.39) | MGAMGAASIMGAM2RPS6KA3 | |
| SCHEMBL8816985 | 0.72 | ACHE (0.52) | DHODH | |
| SCHEMBL8891044 | 0.71 | MGAM (0.68) | MGAMGAASIMGAM2DHODH | |
| SCHEMBL9259477 | 0.71 | MAPT (0.54) | GAACYP1A2CYP2C19KDM4ENPC1 | |
| SCHEMBL8818574 | 0.70 | GAA (0.64) | MGAMGAASIMGAM2DHODH | |
| SCHEMBL8817536 | 0.69 | NR1I3 (0.58) | MGAMGAASIMGAM2RPS6KA3 | |
| SCHEMBL8817053 | 0.69 | DHODH (0.65) | MGAMGAASIMGAM2RPS6KA3 | |
| SCHEMBL4457030 | 0.68 | DHODH (0.53) | MGAMGAASIMGAM2DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997033873-A1 | METHODS OF TREATING OR PREVENTING INTERSTITIAL CYSTITIS | ELI LILLY AND COMPANY (US) | 1997-09-18 | — | — | WO | disclosed |
| WO-1997031635-A1 | METHODS OF TREATING OR PREVENTING SLEEP APNEA | ELI LILLY AND COMPANY (US) | 1997-09-04 | — | — | WO | disclosed |