Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 2/20 | 0.34 |
| ▸ | SCD | O00767 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | PTGES | O14684 | 2/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.31 |
| ▸ | DHODH | Q02127 | 2/20 | 0.30 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
| ▸ | ABL1 | P00519 | 1/20 | 0.30 |
| ▸ | SRC | P12931 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8816922 | 0.87 | ACHE (0.43) | PRMT5MGAMGAASIMGAM2 | |
| SCHEMBL8818782 | 0.87 | KDM4E (0.35) | PRMT5MGAMGAASIMGAM2 | |
| SCHEMBL8814977 | 0.87 | ACHE (0.46) | PRMT5SCDTRPV1MGAMGAA | |
| SCHEMBL8816636 | 0.86 | ACHE (0.39) | PRMT5MGAMGAASIMGAM2 | |
| SCHEMBL8814922 | 0.86 | BRD4 (0.39) | PRMT5GAADHODHPARP1 | |
| SCHEMBL8814868 | 0.86 | PRMT5 (0.32) | PRMT5SCDTRPV1PTGESMGAM | |
| SCHEMBL8079568 | 0.80 | ACHE (0.46) | PRMT5DHODHPARP1 | |
| SCHEMBL8814846 | 0.80 | MGAM (0.39) | PRMT5TRPV1PTGESMGAMGAA | |
| SCHEMBL8818545 | 0.77 | DYRK3 (0.45) | PTGESMGAMGAASIMGAM2 | |
| SCHEMBL8818801 | 0.77 | ACHE (0.44) | PRMT5SCDPTGESMGAMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997031635-A1 | METHODS OF TREATING OR PREVENTING SLEEP APNEA | ELI LILLY AND COMPANY (US) | 1997-09-04 | — | — | WO | disclosed |