Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | PTGES | O14684 | 1/20 | 0.31 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.31 |
| ▸ | SCD | O00767 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8817526 | 0.90 | NR1I3 (0.34) | PRMT5TRPV1PTGESCHEK1KCNH2 | |
| SCHEMBL8814966 | 0.88 | KDM4E (0.35) | PRMT5MGAMGAASIMGAM2 | |
| SCHEMBL8817000 | 0.86 | PRMT5 (0.34) | PRMT5TRPV1PTGESMGAMGAA | |
| SCHEMBL8816922 | 0.85 | ACHE (0.43) | PRMT5MGAMGAASIMGAM2 | |
| SCHEMBL8816636 | 0.84 | ACHE (0.39) | PRMT5MGAMGAASIMGAM2 | |
| SCHEMBL8814977 | 0.83 | ACHE (0.46) | PRMT5TRPV1MGAMGAASI | |
| SCHEMBL8814846 | 0.79 | MGAM (0.39) | PRMT5TRPV1PTGESMGAMGAA | |
| SCHEMBL8818534 | 0.78 | PTGES (0.38) | PTGESMGAMGAASIMGAM2 | |
| SCHEMBL8818537 | 0.77 | RPS6KA3 (0.34) | — | |
| SCHEMBL8079568 | 0.76 | ACHE (0.46) | PRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997031635-A1 | METHODS OF TREATING OR PREVENTING SLEEP APNEA | ELI LILLY AND COMPANY (US) | 1997-09-04 | — | — | WO | disclosed |