Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRNP | P04156 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.48 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | MGAM | O43451 | 1/20 | 0.46 |
| ▸ | SI | P14410 | 1/20 | 0.46 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 3/20 | 0.44 |
| ▸ | RHEB | Q15382 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9015054 | 0.90 | PRNP (0.46) | PRNPMAPTGRIN1GRIN2BGAA | |
| SCHEMBL11198298 | 0.87 | MGAM (0.48) | PRNPMAPTGAAMGAMSI | |
| SCHEMBL456478 | 0.83 | HTT (0.49) | PRNPMAPTGRIN2BALDH1A1HTR6 | |
| SCHEMBL9015051 | 0.80 | RAB9A (0.43) | PRNPMAPTGRIN1GRIN2BGAA | |
| SCHEMBL162159 | 0.80 | LTA4H (0.41) | PRNPMAPTHTR6 | |
| SCHEMBL10690713 | 0.79 | GAA (0.47) | GRIN1GRIN2BGAANPC1ALDH1A1 | |
| SCHEMBL8816632 | 0.78 | MGAM (0.56) | GRIN2BGAAMGAMSIMGAM2 | |
| SCHEMBL6686102 | 0.77 | MGAM (0.62) | MAPTGRIN2BGAAMGAMSI | |
| SCHEMBL721860 | 0.76 | GAA (0.75) | PRNPMAPTGRIN1GRIN2BGAA | |
| SCHEMBL9307952 | 0.75 | NPC1 (0.46) | GRIN1GRIN2BGAAMGAMSI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997031635-A1 | METHODS OF TREATING OR PREVENTING SLEEP APNEA | ELI LILLY AND COMPANY (US) | 1997-09-04 | — | — | WO | disclosed |