Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 17/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL876202 | 0.78 | MAP3K12 (0.50) | ALOX5APMAP4K4 | |
| SCHEMBL12940515 | 0.78 | ALOX5AP (0.50) | ALOX5AP | |
| Hydrochloric Acid SCHEMBL12802443 | 0.76 | ALOX5AP (0.49) | ALOX5AP | |
| SCHEMBL10155426 | 0.74 | ALOX5AP (0.40) | ALOX5APLMNAMAPTHSD11B1 | |
| SCHEMBL19402094 | 0.74 | LTA4H (0.44) | HSD11B1MAP4K4 | |
| SCHEMBL16545978 | 0.73 | NOS3 (0.42) | MAPT | |
| SCHEMBL12967389 | 0.73 | AKT1 (0.30) | — | |
| SCHEMBL881806 | 0.73 | ADRA2A (0.35) | — | |
| SCHEMBL10156248 | 0.70 | ALOX5AP (0.51) | ALOX5AP | |
| SCHEMBL27869063 | 0.70 | MKNK1 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012040139-A1 | OXADIAZOLE INHIBITORS OF LEUKOTRIENE PRODUCTION | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-03-29 | — | — | WO | disclosed |