Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | ACACA | Q13085 | 1/20 | 0.52 |
| ▸ | ABCG2 | Q9UNQ0 | 9/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 5/20 | 0.50 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.50 |
| ▸ | WHR1 | P49842 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | DHODH | Q02127 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | GUSB | P08236 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8818033 | 0.93 | WHR1 (0.45) | L3MBTL1ACACAABCG2ABCB1ABCC1 | |
| SCHEMBL8816999 | 0.90 | ABCG2 (0.47) | L3MBTL1ACACAABCG2ABCB1ABCC1 | |
| SCHEMBL8816575 | 0.84 | ADORA2A (0.62) | ABCG2ABCB1SMN1; SMN2MAPTTP53 | |
| SCHEMBL8818254 | 0.84 | ADORA2A (0.58) | L3MBTL1ACACAABCG2MAPTKDM4E | |
| SCHEMBL8815687 | 0.84 | TGFBR1 (0.49) | KDM4ENPC1ALDH1A1 | |
| SCHEMBL8819429 | 0.83 | TGFBR1 (0.48) | — | |
| SCHEMBL8815416 | 0.82 | KMT2A (0.47) | ACACAABCG2ABCB1TP53ALDH1A1 | |
| SCHEMBL6120916 | 0.82 | TGFBR1 (0.54) | KDM4EALDH1A1 | |
| SCHEMBL8816582 | 0.81 | ADORA2A (0.58) | SMN1; SMN2MAPTTP53KDM4EALDH1A1 | |
| SCHEMBL8815721 | 0.81 | KDM4E (0.53) | L3MBTL1SMN1; SMN2MAPTTP53KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012066122-A1 | 2 - (PYRIDIN- 2 -YL) -QUINAZOLINE DERIVATIVES AND THEIR USE AS MICROBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-05-24 | — | — | WO | disclosed |