Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CCR2 | P41597 | 4/20 | 0.44 |
| ▸ | NAMPT | P43490 | 3/20 | 0.43 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.41 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.41 |
| ▸ | HTR3B | O95264 | 1/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.41 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30543083 | 1.00 | CA1 (0.45) | CA1CA2CCR2NAMPTMEP1B | |
| SCHEMBL15563090 | 1.00 | CA1 (0.45) | CA1CA2CCR2NAMPTMEP1B | |
| SCHEMBL6209362 | 0.82 | MEP1B (0.54) | CA1CA2CCR2NAMPTMEP1B | |
| SCHEMBL23270205 | 0.81 | MAPT (0.54) | CCR2TSHRMAPT | |
| SCHEMBL23270214 | 0.81 | TSHR (0.44) | CA1CA2CCR2NAMPTMEP1B | |
| SCHEMBL881834 | 0.81 | HTR3E (0.56) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL16904074 | 0.79 | CA1 (0.49) | CA1CA2CCR2SMN1; SMN2POLB | |
| SCHEMBL21378325 | 0.78 | HSD17B10 (0.41) | CCR2NAMPTTSHRSMN1; SMN2POLB | |
| SCHEMBL30543084 | 0.78 | HSD17B10 (0.41) | CCR2NAMPTTSHRSMN1; SMN2POLB | |
| SCHEMBL483832 | 0.77 | CA1 (0.70) | CA1CA2TSHRPOLBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111372579-B | Substituted phenylsulfonyl phenyltriazolethiones and use thereof | 神经孔疗法股份有限公司 | 2023-08-22 | — | — | CN | disclosed |