Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | PLK1 | P53350 | 5/20 | 0.47 |
| ▸ | KAT8 | Q9H7Z6 | 4/20 | 0.47 |
| ▸ | BID | P55957 | 3/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.47 |
| ▸ | PPARA | Q07869 | 3/20 | 0.47 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.47 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.47 |
| ▸ | PPARG | P37231 | 2/20 | 0.47 |
| ▸ | EP300 | Q09472 | 1/20 | 0.47 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.47 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.47 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.47 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | RARB | P10826 | 1/20 | 0.46 |
| ▸ | PLK3 | Q9H4B4 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6895810 | 0.94 | GABRP (0.49) | ALDH1A1HSD17B10KDM4EPOLBPLK1 | |
| SCHEMBL14836221 | 0.89 | KAT8 (0.53) | ALDH1A1PLK1KAT8BIDMCL1 | |
| SCHEMBL27924691 | 0.89 | KAT8 (0.53) | ALDH1A1PLK1KAT8BIDMCL1 | |
| SCHEMBL27924694 | 0.89 | KAT8 (0.53) | ALDH1A1PLK1KAT8BIDMCL1 | |
| SCHEMBL28103139 | 0.89 | KAT8 (0.53) | ALDH1A1PLK1KAT8BIDMCL1 | |
| SCHEMBL8757448 | 0.89 | KAT8 (0.53) | ALDH1A1PLK1KAT8BIDMCL1 | |
| SCHEMBL27944038 | 0.89 | KAT8 (0.53) | ALDH1A1PLK1KAT8BIDMCL1 | |
| SCHEMBL27944047 | 0.89 | KAT8 (0.53) | ALDH1A1PLK1KAT8BIDMCL1 | |
| SCHEMBL27944035 | 0.89 | KAT8 (0.53) | ALDH1A1PLK1KAT8BIDMCL1 | |
| SCHEMBL5135888 | 0.87 | MMP2 (0.52) | ALDH1A1HSD17B10KDM4EPOLBMMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997030019-A1 | ANILINE DERIVATIVES HAVING ANTIHYPERGLYCEMIC ACTIVITY | SHAMAN PHARMACEUTICALS, INC. (US) | 1997-08-21 | — | — | WO | disclosed |