Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 2/20 | 0.49 |
| ▸ | GABRD | O14764 | 2/20 | 0.49 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.49 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.49 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.49 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.49 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.49 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.49 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.49 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.49 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.49 |
| ▸ | GABRE | P78334 | 2/20 | 0.49 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.49 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.49 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.49 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.49 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8818591 | 0.94 | ALDH1A1 (0.49) | MMP2HSD17B10ALDH1A1KDM4EPOLB | |
| SCHEMBL5135888 | 0.90 | MMP2 (0.52) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL679426 | 0.88 | TSHR (0.49) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL6258469 | 0.87 | ALDH1A1 (0.46) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL27976077 | 0.86 | TSHR (0.47) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL6859420 | 0.83 | KDM4E (0.52) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL27778033 | 0.83 | PLK1 (0.46) | HSD17B10ALDH1A1KDM4EPOLBNPC1 | |
| SCHEMBL1126873 | 0.82 | MMP2 (0.55) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL27297604 | 0.82 | PLK1 (0.50) | TSHRCA12CA9PLK1RARB | |
| SCHEMBL10903924 | 0.82 | CYP3A4 (0.48) | HSD17B10ALDH1A1KDM4EPOLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1171519-B1 | POLYACETAL RESINS WITH REDUCED FORMALDEHYDE ODOR | DU PONT (US) | 2004-02-11 | — | — | EP | claimed |
| CN-102844305-B | Antibacterial isoquinolin-3-ylurea derivatives | ACTELION PHARMACEUTICALS LTD | 2014-07-02 | — | — | CN | disclosed |
| CN-102844305-A | Antibacterial isoquinolin-3-ylurea derivatives | ACTELION PHARMACEUTICALS LTD | 2012-12-26 | — | — | CN | disclosed |
| CN-101125155-B | Application of erigeron breviscapus methanol extracts in skin-whitening and speckle eliminating prevention | UNIV SICHUAN | 2010-11-10 | — | — | CN | disclosed |
| CN-100411622-C | Melanogenesis inhibitors and whitening agents comprising ergosterol derivative and compositions containing ergosterol derivative | SAKAMOTO BIO CO LTD (JP) | 2008-08-20 | — | — | CN | disclosed |
| CN-101125155-A | Application of erigeron breviscapus methanol extracts in skin-whitening and speckle eliminating prevention | UNIV SICHUAN (CN) | 2008-02-20 | — | — | CN | disclosed |
| CN-101010314-A | Substituted cyclic urea derivatives, preparation thereof and pharmaceutical use thereof as kinase inhibitors | AVENTIS PHARMA SA (FR) | 2007-08-01 | — | — | CN | disclosed |
| CN-1468086-A | Melanogenesis inhibitor and whitening agent prepared from ergosterol derivative, and composition containing ergosterol derivative | ƽ | 2004-01-14 | — | — | CN | disclosed |