Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | GUSB | P08236 | 1/20 | 0.46 |
| ▸ | TGFBR1 | P36897 | 10/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8818575 | 0.88 | ADORA2A (0.43) | MEN1KMT2ATGFBR1MAPK14HPGD | |
| SCHEMBL8816388 | 0.87 | TGFBR1 (0.43) | MEN1KMT2ATGFBR1MAPK14HPGD | |
| SCHEMBL8816582 | 0.86 | ADORA2A (0.58) | MEN1KMT2ATGFBR1MAPK14HPGD | |
| SCHEMBL8817142 | 0.81 | TGFBR1 (0.47) | TGFBR1MAPK14ALDH1A1TSHRADORA2A | |
| SCHEMBL8818624 | 0.81 | GAA (0.51) | MEN1KMT2APOLBGUSBTGFBR1 | |
| SCHEMBL8818694 | 0.81 | ADORA2A (0.48) | MEN1KMT2ATGFBR1MAPK14KDM4E | |
| SCHEMBL8815685 | 0.81 | TGFBR1 (0.51) | TGFBR1MAPK14ALDH1A1ADORA2A | |
| SCHEMBL8818444 | 0.81 | ADORA2A (0.56) | MEN1KMT2ATGFBR1MAPK14ALDH1A1 | |
| SCHEMBL8818479 | 0.80 | ADORA2A (0.47) | MEN1KMT2ATGFBR1MAPK14HPGD | |
| SCHEMBL8818328 | 0.79 | TP53 (0.50) | MEN1KMT2ATGFBR1MAPK14HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012066122-A1 | 2 - (PYRIDIN- 2 -YL) -QUINAZOLINE DERIVATIVES AND THEIR USE AS MICROBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-05-24 | — | — | WO | disclosed |