Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.47 |
| ▸ | TGFBR1 | P36897 | 9/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | ACP1 | P24666 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.41 |
| ▸ | AHR | P35869 | 2/20 | 0.41 |
| ▸ | NR1I3 | Q14994 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.41 |
| ▸ | VDR | P11473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8816502 | 0.91 | MAPT (0.43) | GRM2TGFBR1MAPK14ACP1CYP1A2 | |
| SCHEMBL8817333 | 0.89 | CRHR1 (0.46) | TGFBR1MAPK14ACP1CYP1A2CYP3A4 | |
| SCHEMBL8818148 | 0.88 | MEN1 (0.50) | TGFBR1MAPK14ACP1CYP1A2CYP3A4 | |
| SCHEMBL8814815 | 0.87 | TGFBR1 (0.43) | TGFBR1MAPK14ACP1CYP1A2CYP3A4 | |
| SCHEMBL8817528 | 0.86 | TGFBR1 (0.48) | TGFBR1MAPK14ADORA2A | |
| SCHEMBL8815721 | 0.85 | KDM4E (0.53) | TGFBR1MAPK14ACP1CYP1A2CYP3A4 | |
| SCHEMBL8814824 | 0.85 | TGFBR1 (0.45) | GRM2TGFBR1MAPK14ACP1NR1I3 | |
| SCHEMBL8818447 | 0.83 | ADORA2A (0.54) | TGFBR1MAPK14MAPTADORA2A | |
| SCHEMBL8816575 | 0.81 | ADORA2A (0.62) | CYP1A2CYP3A4CYP2C9CYP2D6CYP2B6 | |
| SCHEMBL8818254 | 0.81 | ADORA2A (0.58) | TGFBR1MAPK14ACP1CYP1A2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012066122-A1 | 2 - (PYRIDIN- 2 -YL) -QUINAZOLINE DERIVATIVES AND THEIR USE AS MICROBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-05-24 | — | — | WO | disclosed |