Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.53 |
| ▸ | DHODH | Q02127 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 2/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | DRD5 | P21918 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8814893 | 0.92 | ACHE (0.51) | ACHEDHODHLTA4HADORA2AADORA1 | |
| SCHEMBL8817571 | 0.91 | ACHE (0.52) | ACHEDHODHLTA4HADORA2AADORA1 | |
| SCHEMBL8816605 | 0.91 | ACHE (0.52) | ACHEDHODHLTA4HADORA2AADORA1 | |
| SCHEMBL8082562 | 0.85 | DRD1 (0.47) | ACHEDHODHLTA4HADORA2AADORA1 | |
| SCHEMBL8891323 | 0.83 | DHODH (0.42) | DHODHNPC1RAB9A | |
| SCHEMBL8818920 | 0.83 | DHODH (0.42) | DHODHNPC1RAB9A | |
| SCHEMBL8818678 | 0.81 | DYRK3 (0.48) | ACHEDHODHLTA4HADORA2AADORA1 | |
| SCHEMBL8819001 | 0.81 | CHEK2 (0.44) | ACHEDHODHLTA4HNPC1RAB9A | |
| SCHEMBL8816926 | 0.80 | ACHE (0.41) | ACHEDHODHLTA4HNPC1RAB9A | |
| SCHEMBL8082476 | 0.80 | ACHE (0.49) | ACHEDHODHLTA4HADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997031635-A1 | METHODS OF TREATING OR PREVENTING SLEEP APNEA | ELI LILLY AND COMPANY (US) | 1997-09-04 | — | — | WO | disclosed |