Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 7/20 | 0.42 |
| ▸ | MGAM | O43451 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | SI | P14410 | 2/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.41 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 2/20 | 0.38 |
| ▸ | MMP9 | P14780 | 2/20 | 0.38 |
| ▸ | MMP8 | P22894 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8818920 | 0.96 | DHODH (0.42) | DHODHMGAMGAASIMGAM2 | |
| SCHEMBL8818678 | 0.88 | DYRK3 (0.48) | DHODHMGAMGAASIMGAM2 | |
| SCHEMBL8819001 | 0.87 | CHEK2 (0.44) | DHODHMGAMGAASIMGAM2 | |
| SCHEMBL8816926 | 0.87 | ACHE (0.41) | DHODHMGAMGAASIMGAM2 | |
| SCHEMBL8082476 | 0.87 | ACHE (0.49) | DHODHMGAMGAASIMGAM2 | |
| SCHEMBL8817561 | 0.85 | PPARG (0.40) | DHODHMGAMGAASIMGAM2 | |
| SCHEMBL8814893 | 0.85 | ACHE (0.51) | DHODH | |
| SCHEMBL8816605 | 0.84 | ACHE (0.52) | DHODHL3MBTL1KDM4E | |
| SCHEMBL8817571 | 0.84 | ACHE (0.52) | DHODHL3MBTL1KDM4E | |
| SCHEMBL8818817 | 0.83 | ACHE (0.53) | DHODHNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997033873-A1 | METHODS OF TREATING OR PREVENTING INTERSTITIAL CYSTITIS | ELI LILLY AND COMPANY (US) | 1997-09-18 | — | — | WO | disclosed |