Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 12/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6935877 | 0.83 | ACHE (0.62) | ACHEALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL29389102 | 0.73 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2NFE2L2KDM4EPTGS2 | |
| SCHEMBL48607 | 0.73 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2NFE2L2KDM4EPTGS2 | |
| SCHEMBL7041619 | 0.72 | ACHE (0.61) | ACHEALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL4808094 | 0.71 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2NFE2L2KDM4EPTGS2 | |
| Vanillin SCHEMBL7534461 | 0.70 | ACHE (0.73) | ACHEALDH1A1MEN1KMT2AKDM4E | |
| Hydrazine SCHEMBL27687525 | 0.69 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2NFE2L2KDM4EPTGS2 | |
| SCHEMBL6938768 | 0.69 | ACHE (0.76) | ACHE | |
| SCHEMBL16913351 | 0.69 | ACHE (0.76) | ACHE | |
| SCHEMBL569403 | 0.67 | ACHE (0.74) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997047295-A1 | SUBSTITUTED METHOXY BENZYLIDENE INDENYL-ACETIC AND PROPIONIC ACIDS FOR TREATING PATIENTS WITH PRECANCEROUS LESIONS | CELL PATHWAYS, INC. (US) | 1997-12-18 | — | — | WO | disclosed |