Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 4/20 | 0.62 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.59 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.59 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.59 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.59 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.59 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.59 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.59 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.57 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.57 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9473464 | 0.80 | ALDH1A1 (0.58) | KMT2AMAPTLMNAMEN1HDAC3 | |
| Hydrochloric Acid SCHEMBL9474147 | 0.79 | ALDH1A1 (0.57) | KMT2AMAPTLMNAMEN1HDAC3 | |
| SCHEMBL14249309 | 0.77 | HDAC3 (0.71) | KMT2AMAPTLMNAMEN1HDAC3 | |
| SCHEMBL4669452 | 0.77 | LMNA (1.00) | KMT2AMAPTLMNAMEN1HDAC3 | |
| SCHEMBL2843958 | 0.75 | HDAC4 (1.00) | KMT2AMAPTLMNAMEN1HDAC3 | |
| SCHEMBL217745 | 0.74 | HDAC3 (0.71) | KMT2AMAPTLMNAMEN1HDAC3 | |
| SCHEMBL8819216 | 0.74 | KMT2A (0.60) | KMT2AMAPTLMNAMEN1HDAC3 | |
| SCHEMBL6695263 | 0.72 | HDAC3 (0.69) | KMT2AMAPTLMNAMEN1HDAC3 | |
| SCHEMBL12513866 | 0.72 | KMT2A (0.67) | KMT2AMAPTLMNAMEN1HDAC3 | |
| SCHEMBL6867060 | 0.72 | KMT2A (0.62) | KMT2AMAPTLMNAMEN1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997046549-A1 | ANTI-NEURODEGENERATIVELY EFFECTIVE XANTHENE DERIVATIVES | NOVARTIS AG (CH) | 1997-12-11 | — | — | WO | claimed |
| WO-1997046549-A1 | ANTI-NEURODEGENERATIVELY EFFECTIVE XANTHENE DERIVATIVES | NOVARTIS AG (CH) | 1997-12-11 | — | — | WO | disclosed |