Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8819203 | 0.80 | TSHR (0.71) | MAOAMAOBTSHRNPSR1LMNA | |
| SCHEMBL8819880 | 0.79 | TSHR (0.69) | TSHRNPSR1LMNATP53ATM | |
| SCHEMBL8820505 | 0.76 | HDAC3 (0.44) | MAOAMAOBTSHRNPSR1LMNA | |
| SCHEMBL28984773 | 0.74 | ATM (0.59) | MAOAMAOBTSHRNPSR1LMNA | |
| SCHEMBL30416067 | 0.74 | ATM (0.59) | MAOAMAOBTSHRNPSR1LMNA | |
| SCHEMBL8815562 | 0.71 | ATM (0.55) | MAOAMAOBTSHRNPSR1LMNA | |
| SCHEMBL27851767 | 0.69 | TSHR (0.59) | MAOAMAOBTSHRNPSR1LMNA | |
| SCHEMBL11861840 | 0.68 | TSHR (0.61) | MAOAMAOBTSHRNPSR1LMNA | |
| Xanthene Carboxylic Acid SCHEMBL2807858 | 0.68 | ATM (0.61) | MAOAMAOBTSHRNPSR1LMNA | |
| Hydrochloric Acid SCHEMBL27833742 | 0.68 | TSHR (0.57) | MAOAMAOBTSHRNPSR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997046549-A1 | ANTI-NEURODEGENERATIVELY EFFECTIVE XANTHENE DERIVATIVES | NOVARTIS AG (CH) | 1997-12-11 | — | — | WO | claimed |