Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.47 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8820531 | 1.00 | LMNA (0.50) | LMNASMN1; SMN2TAS1R3TAS1R1MEN1 | |
| SCHEMBL9556205 | 0.86 | L3MBTL1 (0.59) | LMNASMN1; SMN2KMT2AMAPTCYP1A2 | |
| SCHEMBL9556198 | 0.86 | L3MBTL1 (0.59) | LMNASMN1; SMN2KMT2AMAPTCYP1A2 | |
| SCHEMBL16691198 | 0.85 | HDAC1 (0.47) | TAS1R3TAS1R1KMT2AL3MBTL1CA12 | |
| SCHEMBL8819493 | 0.83 | GRM5 (0.43) | TAS1R3TAS1R1KMT2AL3MBTL1RAB9A | |
| SCHEMBL4680782 | 0.80 | LMNA (0.52) | LMNASMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL4678063 | 0.80 | LMNA (0.49) | LMNASMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL8820790 | 0.80 | GRM5 (0.45) | TAS1R3TAS1R1L3MBTL1CA12CA1 | |
| SCHEMBL6029601 | 0.80 | RAB9A (0.64) | LMNASMN1; SMN2CYP2C9CYP2C19L3MBTL1 | |
| SCHEMBL8972761 | 0.79 | L3MBTL1 (0.52) | TAS1R3TAS1R1L3MBTL1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997049705-A1 | 5,6,7,8-TETRAHYDROPYRIDO[2,3-d]PYRIMIDINE DERIVATIVES | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 1997-12-31 | — | — | WO | disclosed |