Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.46 |
| ▸ | RAB9A | P51151 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7761248 | 0.78 | KMT2A (0.45) | ALDH1A1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL283726 | 0.76 | CYP19A1 (0.42) | ALDH1A1MAPK1L3MBTL1CYP1A2CYP2C9 | |
| SCHEMBL11822854 | 0.74 | ALDH1A1 (0.74) | ALDH1A1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL247444 | 0.74 | RAB9A (0.69) | ALDH1A1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL11822838 | 0.74 | ALDH1A1 (0.74) | ALDH1A1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL347800 | 0.74 | RAB9A (0.69) | ALDH1A1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL247445 | 0.74 | RAB9A (0.69) | ALDH1A1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL4562175 | 0.72 | MAPT (0.67) | ALDH1A1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL9803920 | 0.70 | ESR1 (0.68) | ALDH1A1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL11834251 | 0.70 | ESR1 (0.68) | ALDH1A1RAB9AMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997049706-A1 | SUBSTITUTED 7-AMINO-PYRROLO[3,2-d]PYRIMIDINES AND THE USE THEREOF | NOVARTIS AG (CH) | 1997-12-31 | — | — | WO | disclosed |