SCHEMBL8820656

SCHEMBL8820656

O=[N+]([O-])c1ccc(S(=O)(=O)O)c(-c2cccc(-c3ccccc3)c2)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 2/20 0.49
POLB P06746 2/20 0.45
RAB9A P51151 1/20 0.45
PTPRC P08575 3/20 0.44
S100A4 P26447 2/20 0.44
BCHE P06276 1/20 0.44
ACHE P22303 1/20 0.44
CES1 P23141 1/20 0.44
PTGDR2 Q9Y5Y4 1/20 0.44
MAPK1 P28482 2/20 0.43
ALDH1A1 P00352 3/20 0.43
CYP1A2 P05177 1/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2D6 P10635 1/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43
HIF1A Q16665 1/20 0.43
MAPT P10636 2/20 0.42
NPSR1 Q6W5P4 1/20 0.42
NT5E P21589 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11647394 0.91 PTGS2 (0.57) PTGS2POLBRAB9APTPRCS100A4
SCHEMBL8820272 0.84 PTGS2 (0.57) PTGS2POLBRAB9APTPRCS100A4
SCHEMBL2009412 0.81 ALDH1A1 (0.55) RAB9APTPRCALDH1A1MAPTNPSR1
SCHEMBL18298159 0.81 PTGS2 (0.40) PTGS2POLBRAB9APTGDR2CA1
SCHEMBL3618809 0.80 PTGS2 (0.57) PTGS2POLBRAB9APTPRCS100A4
SCHEMBL17557155 0.80 ALDH1A1 (0.47) PTPRCALDH1A1MAPTNPSR1CA1
SCHEMBL4838465 0.80 TSHR (0.51) RAB9AACHEALDH1A1MAPTNPSR1
SCHEMBL11041119 0.77 ACHE (0.49) PTGS2RAB9APTPRCS100A4ACHE
SCHEMBL17978517 0.77 PTGS2 (0.55) PTGS2POLBRAB9APTPRCS100A4
SCHEMBL11041114 0.77 ACHE (0.49) PTGS2RAB9APTPRCS100A4ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1997048677-A1 NON-IONIC PHOTOACID GENERATORS WITH IMPROVED QUANTUM EFFICIENCY PPG INDUSTRIES, INC. (US) 1997-12-24 WO disclosed