Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLRMT | O00411 | 1/20 | 0.45 |
| ▸ | P2RX3 | P56373 | 5/20 | 0.38 |
| ▸ | P2RX4 | Q99571 | 4/20 | 0.38 |
| ▸ | P2RX1 | P51575 | 3/20 | 0.38 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.34 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.34 |
| ▸ | P2RY11 | Q96G91 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10171206 | 0.92 | POLRMT (0.36) | POLRMT | |
| Gs-441326 SCHEMBL10149536 | 0.87 | POLRMT (0.47) | POLRMTP2RX3P2RX4P2RX1P2RX2 | |
| SCHEMBL12464640 | 0.86 | POLRMT (0.45) | POLRMTP2RX3P2RX4P2RX1P2RX2 | |
| SCHEMBL17129838 | 0.83 | POLRMT (0.47) | POLRMTP2RX3P2RX4P2RX1P2RX2 | |
| SCHEMBL17129823 | 0.83 | POLRMT (0.47) | POLRMTP2RX3P2RX4P2RX1P2RX2 | |
| SCHEMBL10142499 | 0.83 | POLRMT (0.47) | POLRMTP2RX3P2RX4P2RX1P2RX2 | |
| SCHEMBL14052088 | 0.83 | POLRMT (0.45) | POLRMTP2RX3P2RX4P2RX1P2RX2 | |
| SCHEMBL881457 | 0.82 | TMPRSS2 (0.34) | — | |
| SCHEMBL24074599 | 0.81 | POLRMT (0.49) | POLRMTP2RX3P2RX4P2RX1P2RX2 | |
| SCHEMBL10141879 | 0.81 | POLRMT (0.47) | POLRMTP2RX3P2RX4P2RX1P2RX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012039791-A1 | 2' -FLUORO SUBSTITUTED CARBA-NUCLEOSIDE ANALOGS FOR ANTIVIRAL TREATMENT | GILEAD SCIENCES, INC. (US) | 2012-03-29 | — | — | WO | disclosed |