Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 10/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.31 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10171206 | 0.86 | POLRMT (0.36) | TMPRSS2PIK3CDRIPK1 | |
| SCHEMBL882157 | 0.82 | POLRMT (0.45) | — | |
| SCHEMBL881677 | 0.82 | TMPRSS2 (0.40) | TMPRSS2PIK3CD | |
| SCHEMBL881706 | 0.81 | RIPK1 (0.36) | RIPK1 | |
| SCHEMBL17215149 | 0.79 | PRMT5 (0.35) | TMPRSS2PIK3CDRIPK1TNK2 | |
| SCHEMBL15682912 | 0.79 | TMPRSS2 (0.41) | TMPRSS2PIK3CD | |
| SCHEMBL18697842 | 0.78 | FAP (0.33) | — | |
| SCHEMBL10120471 | 0.78 | TMPRSS2 (0.42) | TMPRSS2PIK3CD | |
| SCHEMBL12243239 | 0.78 | TMPRSS2 (0.42) | TMPRSS2PIK3CD | |
| SCHEMBL17109563 | 0.78 | TMPRSS2 (0.42) | TMPRSS2PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012039787-A1 | 2' -FLUORO SUBSTITUTED CARBA-NUCLEOSIDE ANALOGS FOR ANTIVIRAL TREATMENT | GILEAD SCIENCES, INC. (US) | 2012-03-29 | — | — | WO | disclosed |