Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.40 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23697940 | 0.83 | TRPM8 (0.52) | TRPM8TRPA1EPHX1TRPV1KCNA5 | |
| SCHEMBL2332511 | 0.79 | TRPM8 (0.44) | TRPM8TRPA1EPHX1TRPV1KCNA5 | |
| SCHEMBL18335724 | 0.78 | TRPM8 (0.50) | TRPM8TRPA1EPHX1TRPV1KCNA5 | |
| SCHEMBL8108333 | 0.77 | TRPM8 (0.46) | TRPM8TRPA1EPHX1TRPV1KCNA5 | |
| SCHEMBL7771959 | 0.77 | TRPM8 (0.42) | TRPM8TRPA1EPHX1TRPV1KCNA5 | |
| SCHEMBL7766515 | 0.77 | TRPM8 (0.42) | TRPM8TRPA1EPHX1TRPV1KCNA5 | |
| SCHEMBL8108330 | 0.76 | TRPM8 (0.44) | TRPM8TRPA1EPHX1TRPV1KCNA5 | |
| SCHEMBL5981087 | 0.76 | TRPM8 (0.48) | TRPM8TRPA1EPHX1TRPV1KCNA5 | |
| SCHEMBL9951821 | 0.74 | EPHX1 (0.49) | TRPM8TRPA1EPHX1TRPV1KCNA5 | |
| SCHEMBL1032282 | 0.74 | EPHX1 (0.49) | TRPM8TRPA1EPHX1TRPV1KCNA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997044341-A1 | CYCLIC POLYAMIDES OF GLUTAMIC ACID AND ASPARTIC ACID WITH ANTI-GASTRIN ACTIVITY, A METHOD FOR THEIR PREPARATION AND THEIR PHARMACEUTICAL USE | ROTTA RESEARCH LABORATORIUM S.P.A. (IT) | 1997-11-27 | — | — | WO | disclosed |