Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2332511 | 0.86 | TRPM8 (0.44) | TRPM8TRPA1OPRM1EPHX1ALDH1A1 | |
| SCHEMBL8821704 | 0.77 | TRPM8 (0.48) | TRPM8TRPA1EPHX1ALDH1A1KCNA5 | |
| SCHEMBL8905470 | 0.77 | OPRM1 (0.43) | TRPM8TRPA1OPRM1EPHX1ALDH1A1 | |
| SCHEMBL6617593 | 0.77 | OPRM1 (0.46) | TRPM8TRPA1OPRM1EPHX1ALDH1A1 | |
| SCHEMBL7770419 | 0.73 | TRPM8 (0.42) | TRPM8TRPA1OPRM1EPHX1ALDH1A1 | |
| SCHEMBL7771959 | 0.73 | TRPM8 (0.42) | TRPM8TRPA1OPRM1EPHX1ALDH1A1 | |
| SCHEMBL5981079 | 0.72 | TRPM8 (0.48) | TRPM8TRPA1OPRM1EPHX1ALDH1A1 | |
| SCHEMBL23697940 | 0.72 | TRPM8 (0.52) | TRPM8TRPA1EPHX1ALDH1A1KCNA5 | |
| SCHEMBL28533035 | 0.71 | EPHX1 (0.46) | TRPM8TRPA1OPRM1EPHX1ALDH1A1 | |
| SCHEMBL5166055 | 0.71 | ALDH1A1 (0.50) | TRPM8TRPA1EPHX1ALDH1A1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6313254-B1 | POLYETHER AND/OR POLYCARBONATE MACRODIOL-DERIVED SOFT SEGMENT; MEDICAL EQUIPMENT, IMPLANTS, PROSTHETICS; ENZYME AND OXIDATION RESISTANCE; CATHETERS | CARDIAC CRC NOMINEES PTY LTD (AU) | 2001-11-06 | — | — | US | disclosed |