SCHEMBL1032282

SCHEMBL1032282

CC1CCC(C(C)C)C(C(C)(C)C(=O)O)C1

nearest known ligand 0.49

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 3/20 0.49
TRPM8 Q7Z2W7 4/20 0.47
TRPA1 O75762 2/20 0.47
TRPV1 Q8NER1 4/20 0.46
KCNA5 P22460 1/20 0.41
CYP19A1 P11511 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9951821 0.86 EPHX1 (0.49) EPHX1TRPM8TRPA1TRPV1KCNA5
SCHEMBL29018734 0.85 EPHX1 (0.47) EPHX1TRPM8TRPA1TRPV1KCNA5
SCHEMBL112084 0.85 EPHX1 (0.47) EPHX1TRPM8TRPA1TRPV1KCNA5
SCHEMBL9950972 0.80 EPHX1 (0.46) EPHX1TRPM8TRPA1TRPV1KCNA5
SCHEMBL15282238 0.80 EPHX1 (0.43) EPHX1TRPM8TRPA1TRPV1KCNA5
Lactic Acid SCHEMBL31239678 0.80 EPHX1 (0.43) EPHX1TRPM8TRPA1TRPV1KCNA5
SCHEMBL7214058 0.79 EPHX1 (0.45) EPHX1TRPM8TRPA1TRPV1KCNA5
SCHEMBL3220592 0.79 TRPM8 (0.44) EPHX1TRPM8TRPA1TRPV1KCNA5
SCHEMBL3220575 0.79 TRPM8 (0.44) EPHX1TRPM8TRPA1TRPV1KCNA5
SCHEMBL584163 0.79 EPHX1 (0.42) EPHX1TRPM8TRPA1TRPV1KCNA5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 510 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3081207-B1 USE OF A LIPOSOME COMPOSITION SYMRISE AG (DE) 2022-09-21 EP claimed
EP-3687311-A1 AMIDES FOR GENERATING A TRIGEMINAL EFFECT Symrise AG (DE) 2020-08-05 EP claimed
EP-3142499-B1 HOMOVANILLIC ACID ESTERS, IN PARTICULAR FOR ACHIEVING AN IMPRESSION OF HEAT AND/OR SPICINESS SYMRISE AG (DE) 2019-10-30 EP claimed
WO-2019063069-A1 AMIDES FOR GENERATING A TRIGEMINAL EFFECT SYMRISE AG (DE) 2019-04-04 WO claimed
EP-3142499-A1 HOMOVANILLIC ESTER, MORE PARTICULARLY FOR ACHIEVING AN IMPRESSION OF HEAT AND/OR SPICINESS Symrise AG (DE) 2017-03-22 EP claimed
WO-2015158677-A1 HOMOVANILLIC ESTER, MORE PARTICULARLY FOR ACHIEVING AN IMPRESSION OF HEAT AND/OR SPICINESS SYMRISE AG (DE) 2015-10-22 WO claimed
EP-2932858-A1 Homovanillic acid esters, in particular for achieving an impression of heat and/or spiciness Symrise AG (DE) 2015-10-21 EP claimed
EP-2008530-B1 Aroma composition for reducing or suppressing unwanted bitter and astringent impressions SYMRISE AG (DE) 2011-01-19 EP claimed
EP-2008530-A1 Aroma composition for reducing or suppressing unwanted bitter and astringent impressions Symrise GmbH & Co. KG (DE) 2008-12-31 EP claimed
EP-4103144-B1 COMPOSITIONS COMPRISING UV-FILTERS AND ONE OR MORE (BIO)-ALKANEDIOLS SYMRISE AG (DE) 2026-05-27 EP disclosed
EP-4110277-B1 COMPOSITIONS COMPRISING (BIO)-ALKANEDIOLS SYMRISE AG (DE) 2026-04-22 EP disclosed
EP-3911172-B1 COMBINATION OF SATIETY COMPONENTS WITH ARGININE SYMRISE AG (DE) 2026-04-15 EP disclosed
EP-3045161-B1 Use of active mixtures of 1,2-hexanediol and 1,2-octanediol in cosmetic, pharmaceutical or dermatological emulsions SYMRISE AG (DE) 2026-03-25 EP disclosed
EP-4025675-B1 A PERFUME OIL MIXTURE SYMRISE AG (DE) 2026-03-18 EP disclosed
EP-1958627-A2 Use of certain menthyl-3-oxocarbonic acid esters as physiological cooling agents Symrise GmbH & Co. KG (DE) 2008-08-20 EP disclosed
EP-1913976-A1 N-alpha-(menthane carbonyl) amino acid amides and their use as physiological coolants Symrise GmbH & Co. KG (DE) 2008-04-23 EP disclosed
EP-1765772-A1 USE OF ALKYLOXYALCANIC ACID AMIDES, IN PARTICULAR IN THE FORM OF AROMATIC SUBSTANCES AND A NOVEL ALKYLOXYALCANIC ACID AMIDE Symrise GmbH & Co. KG (DE) 2007-03-28 EP disclosed
EP-1682489-A1 USE OF ALKENE CARBOXLIC ACID N ALKYLAMIDES AS FLAVOURING AGENTS Symrise GmbH & Co. KG (DE) 2006-07-26 EP disclosed
WO-2006003210-A1 USE OF ALKYLOXYALCANIC ACID AMIDES, IN PARTICULAR IN THE FORM OF AROMATIC SUBSTANCES AND A NOVEL ALKYLOXYALCANIC ACID AMIDE SYMRISE GMBH & CO. KG (DE) 2006-01-12 WO disclosed
WO-2005044778-A1 USE OF ALKENE CARBOXLIC ACID N ALKYLAMIDES AS FLAVOURING AGENTS SYMRISE GMBH & CO. KG (DE) 2005-05-19 WO disclosed