Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.31 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.31 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.31 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.30 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8821862 | 0.84 | DPP7 (0.31) | DPP7GNAI3GNAO1GNAI1 | |
| SCHEMBL7220182 | 0.80 | DPP7 (0.32) | DPP7GNAI3GNAO1GNAI1NOS3 | |
| SCHEMBL2302818 | 0.75 | GSR (0.50) | DPP7GNAI3GNAO1GNAI1 | |
| SCHEMBL2410023 | 0.73 | GSR (0.42) | DPP7GNAI3GNAO1GNAI1 | |
| SCHEMBL2410019 | 0.73 | GSR (0.42) | DPP7GNAI3GNAO1GNAI1 | |
| SCHEMBL8821895 | 0.71 | DPP8 (0.35) | DPP7 | |
| SCHEMBL8821858 | 0.70 | GNAI3 (0.32) | GNAI3GNAO1GNAI1 | |
| SCHEMBL7974904 | 0.70 | DPP7 (0.35) | DPP7GNAI3GNAO1GNAI1 | |
| SCHEMBL27009299 | 0.65 | DPP7 (0.42) | DPP7GNAI3GNAO1GNAI1 | |
| SCHEMBL7220597 | 0.65 | NOS3 (0.31) | NOS3NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997032844-A9 | HYDROXYAMIDINO DERIVATIVES USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | — | 1997-12-24 | — | — | WO | disclosed |