Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 9/20 | 0.37 |
| ▸ | NOS1 | P29475 | 7/20 | 0.37 |
| ▸ | NOS3 | P29474 | 5/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | DDAH1 | O94760 | 4/20 | 0.35 |
| ▸ | GSR | P00390 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8821890 | 0.83 | NOS2 (0.41) | NOS2NOS1NOS3CYP1A2TSHR | |
| SCHEMBL8821873 | 0.83 | NOS2 (0.40) | NOS2NOS1NOS3CYP1A2TSHR | |
| SCHEMBL8821852 | 0.79 | NOS2 (0.41) | NOS2NOS1NOS3CYP1A2TSHR | |
| SCHEMBL8821851 | 0.76 | NOS2 (0.40) | NOS2NOS1NOS3CYP1A2TSHR | |
| SCHEMBL8821859 | 0.74 | PLA2G7 (0.39) | KMT2A | |
| SCHEMBL7909780 | 0.74 | NOS2 (0.42) | NOS2NOS1NOS3CYP1A2TSHR | |
| SCHEMBL7909776 | 0.74 | NOS2 (0.42) | NOS2NOS1NOS3CYP1A2TSHR | |
| SCHEMBL7908808 | 0.70 | NOS2 (0.44) | NOS2NOS1NOS3CYP1A2TSHR | |
| SCHEMBL8821860 | 0.70 | NOS2 (0.35) | NOS2NOS1NOS3CYP1A2TSHR | |
| Aldicarb SCHEMBL2887130 | 0.69 | TDP1 (0.61) | NOS2NOS1NOS3CYP1A2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997032844-A9 | HYDROXYAMIDINO DERIVATIVES USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | — | 1997-12-24 | — | — | WO | claimed |