Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.31 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8752765 | 0.94 | GPBAR1 (0.32) | NR1H4GPBAR1 | |
| SCHEMBL7062537 | 0.85 | ALDH1A1 (0.33) | GPBAR1 | |
| SCHEMBL8822199 | 0.84 | NPC1 (0.34) | NR1H4GPBAR1 | |
| SCHEMBL8822162 | 0.84 | NR1H4 (0.30) | NR1H4GPBAR1 | |
| SCHEMBL8391480 | 0.79 | ALDH1A1 (0.34) | NR1H4GPBAR1 | |
| SCHEMBL7060912 | 0.78 | SMURF2 (0.38) | NR1H4GPBAR1 | |
| SCHEMBL6966959 | 0.75 | ALOX5 (0.34) | NR1H4GPBAR1 | |
| SCHEMBL6560302 | 0.73 | CACNA1B (0.36) | NR1H4 | |
| SCHEMBL8816565 | 0.73 | SLC6A4 (0.39) | SLC6A2SLC6A4 | |
| SCHEMBL8492504 | 0.71 | DHODH (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0560482-B1 | 4-Benzoyl isoxazole derivatives and their use as herbicides | RHONE POULENC AGRICULTURE (GB) | 1997-08-06 | — | — | EP | claimed |