Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMURF2 | Q9HAU4 | 1/20 | 0.38 |
| ▸ | SMURF1 | Q9HCE7 | 1/20 | 0.38 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 13/20 | 0.34 |
| ▸ | FABP1 | P07148 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | CASP3 | P42574 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.30 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.30 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | PPARD | Q03181 | 1/20 | 0.30 |
| ▸ | PPARA | Q07869 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7062537 | 0.86 | ALDH1A1 (0.33) | GPBAR1ALDH1A1HPGDPPARGPPARD | |
| SCHEMBL8492682 | 0.83 | SMURF2 (0.40) | SMURF2SMURF1GPBAR1NR1H4ALDH1A1 | |
| SCHEMBL8822174 | 0.82 | SMURF2 (0.38) | SMURF2SMURF1GPBAR1NR1H4FABP1 | |
| SCHEMBL8822184 | 0.81 | SMURF2 (0.37) | SMURF2SMURF1GPBAR1NR1H4FABP1 | |
| SCHEMBL8762864 | 0.80 | SMURF2 (0.38) | SMURF2SMURF1GPBAR1NR1H4ALDH1A1 | |
| SCHEMBL8391480 | 0.79 | ALDH1A1 (0.34) | GPBAR1NR1H4ALDH1A1HPGDNPSR1 | |
| SCHEMBL8762928 | 0.78 | SMURF2 (0.36) | SMURF2SMURF1GPBAR1NR1H4HPGD | |
| SCHEMBL8822166 | 0.78 | NR1H4 (0.31) | GPBAR1NR1H4 | |
| SCHEMBL8492504 | 0.77 | DHODH (0.35) | ALDH1A1HPGDCASP3RAB9ASMN1; SMN2 | |
| SCHEMBL27789070 | 0.76 | SMURF2 (0.40) | SMURF2SMURF1GPBAR1NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1124421-B1 | NOVEL HERBICIDE COMPOSITIONS BASED ON GLYPHOSATES AND ISOXAZOLES | BAYER CROPSCIENCE SA (FR) | 2003-05-21 | — | — | EP | claimed |
| EP-1124421-A1 | NOVEL HERBICIDE COMPOSITIONS BASED ON GLYPHOSATES AND ISOXAZOLES | AVENTIS CROPSCIENCE S.A. (FR) | 2001-08-22 | — | — | EP | claimed |
| WO-2000025584-A1 | NOVEL HERBICIDE COMPOSITIONS BASED ON GLYPHOSATES AND ISOXAZOLES | AVENTIS CROPSCIENCE S.A. (FR) | 2000-05-11 | — | — | WO | claimed |
| EP-0560482-B1 | 4-Benzoyl isoxazole derivatives and their use as herbicides | RHONE POULENC AGRICULTURE (GB) | 1997-08-06 | — | — | EP | claimed |
| EP-1124421-B1 | NOVEL HERBICIDE COMPOSITIONS BASED ON GLYPHOSATES AND ISOXAZOLES | BAYER CROPSCIENCE SA (FR) | 2003-05-21 | — | — | EP | disclosed |
| EP-1124421-A1 | NOVEL HERBICIDE COMPOSITIONS BASED ON GLYPHOSATES AND ISOXAZOLES | AVENTIS CROPSCIENCE S.A. (FR) | 2001-08-22 | — | — | EP | disclosed |
| WO-2000025584-A1 | NOVEL HERBICIDE COMPOSITIONS BASED ON GLYPHOSATES AND ISOXAZOLES | AVENTIS CROPSCIENCE S.A. (FR) | 2000-05-11 | — | — | WO | disclosed |