Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | PGR | P06401 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | PTGER2 | P43116 | 8/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 5/20 | 0.42 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.41 |
| ▸ | PTGIR | P43119 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.40 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8822889 | 1.00 | ALDH1A1 (0.44) | ALDH1A1PGRLMNAPOLBMAPT | |
| SCHEMBL8822847 | 0.91 | PGR (0.46) | ALDH1A1PGRLMNAPOLBMAPT | |
| SCHEMBL8822853 | 0.91 | PGR (0.46) | ALDH1A1PGRLMNAPOLBMAPT | |
| SCHEMBL8822839 | 0.90 | PTGDR2 (0.50) | ALDH1A1PGRPTGER2PTGER4PTGER3 | |
| SCHEMBL8822843 | 0.90 | PTGDR2 (0.50) | ALDH1A1PGRPTGER2PTGER4PTGER3 | |
| SCHEMBL8822840 | 0.86 | LMNA (0.52) | ALDH1A1PGRLMNAPOLBMAPT | |
| SCHEMBL8822962 | 0.86 | PTGDR2 (0.52) | ALDH1A1PGRPTGER2PTGER4PTGER3 | |
| SCHEMBL8822956 | 0.86 | PTGDR2 (0.52) | ALDH1A1PGRPTGER2PTGER4PTGER3 | |
| SCHEMBL8822844 | 0.83 | PTGDR2 (0.52) | ALDH1A1PGRPTGER2PTGER4PTGER3 | |
| SCHEMBL8822841 | 0.83 | PTGDR2 (0.52) | ALDH1A1PGRPTGER2PTGER4PTGER3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0454429-B1 | Use of 15-dehydroxy-16-oxoprostaglandin derivatives in the treatment of allergic diseases | R TECH UENO LTD (JP) | 1997-01-29 | — | — | EP | disclosed |
| US-5221799-A | New 15-dehydroxy-16-oxoprostaglandins | K.K. UENO SEIYAKU OYO KENKYUJO (JP) | 1993-06-22 | — | — | US | disclosed |
| EP-0454429-A2 | Use of 15-dehydroxy-16-oxoprostaglandin derivatives in the treatment of allergic diseases | Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) | 1991-10-30 | — | — | EP | disclosed |
| EP-0444844-A2 | New 15-dehydroxy-16-oxoprostaglandins | R-TECH UENO LTD. (JP) | 1991-09-04 | — | — | EP | disclosed |