Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.41 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.41 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8823094 | 0.91 | TDP1 (0.43) | ALDH1A1HPGDRAB9AMEN1KMT2A | |
| SCHEMBL8823071 | 0.86 | RAB9A (0.41) | ALDH1A1GAAHPGDNPC1RAB9A | |
| SCHEMBL8823066 | 0.81 | NTRK1 (0.51) | KMT2ALMNA | |
| SCHEMBL8946722 | 0.81 | PIK3CA (0.44) | ALDH1A1GAAMAPTMTORTDP1 | |
| SCHEMBL8823064 | 0.79 | KDM4E (0.47) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL8823045 | 0.79 | LPAR1 (0.40) | KMT2ALMNA | |
| SCHEMBL8823096 | 0.79 | LPAR1 (0.40) | ALDH1A1HPGDRAB9AMEN1KMT2A | |
| SCHEMBL8823127 | 0.77 | LPAR1 (0.38) | ALDH1A1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL8823162 | 0.75 | — | — | |
| SCHEMBL8823120 | 0.73 | ALDH1A1 (0.58) | ALDH1A1GAAHPGDNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0761658-A1 | Azole-phenyl urea derivatives as ACAT inhibitors and their production | NIHON NOHYAKU CO., LTD. (JP) | 1997-03-12 | — | — | EP | disclosed |