SCHEMBL8823293

CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CC(N)=O)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 5)

	gene	UniProt	supporting neighbours	confidence
▸	KISS1R	Q969F8	6/20	0.54

▸	OPRD1	P41143	2/20	0.51

▸	OPRM1	P35372	1/20	0.51

▸	BACE1	P56817	2/20	0.48

▸	ACE	P12821	1/20	0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL8823292	1.00	KISS1R (0.54)	KISS1ROPRD1OPRM1BACE1ACE
SCHEMBL29804901	0.92	KISS1R (0.57)	KISS1ROPRD1OPRM1BACE1
SCHEMBL29804796	0.91	ACE (0.50)	KISS1ROPRD1OPRM1BACE1ACE
SCHEMBL30168671	0.91	ACE (0.52)	KISS1ROPRD1OPRM1ACE
SCHEMBL30638818	0.90	ACE (0.55)	KISS1ROPRD1OPRM1ACE
SCHEMBL31174215	0.88	BACE1 (0.51)	KISS1ROPRD1OPRM1BACE1ACE
SCHEMBL31514356	0.88	KISS1R (0.54)	KISS1RBACE1ACE
SCHEMBL31326113	0.88	KISS1R (0.54)	KISS1ROPRD1BACE1ACE
SCHEMBL30477367	0.86	OPRM1 (0.51)	KISS1ROPRD1OPRM1BACE1ACE
SCHEMBL30932060	0.86	KISS1R (0.55)	KISS1RBACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-0367566-B1	Interleukin-4 receptors	IMMUNEX CORP (US)	1997-05-14	—	—	EP	disclosed
EP-0367566-A1	Interleukin-4 receptors	IMMUNEX CORPORATION (US)	1990-05-09	—	—	EP	disclosed