SCHEMBL29804901

SCHEMBL29804901

CC[C@H](C)[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc1ccccc1)[C@@H](C)CC)C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ KISS1R Q969F8 2/20 0.57
▸ OPRD1 P41143 9/20 0.55
▸ OPRM1 P35372 7/20 0.55
▸ CTSD P07339 2/20 0.51
▸ BACE1 P56817 2/20 0.49
▸ OPRK1 P41145 2/20 0.49
▸ BACE2 Q9Y5Z0 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8823292 0.92 KISS1R (0.54) KISS1ROPRD1OPRM1BACE1
SCHEMBL8823293 0.92 KISS1R (0.54) KISS1ROPRD1OPRM1BACE1
SCHEMBL29804796 0.92 ACE (0.50) KISS1ROPRD1OPRM1CTSDBACE1
SCHEMBL30168671 0.90 ACE (0.52) KISS1ROPRD1OPRM1CTSD
SCHEMBL30272520 0.90 OPRD1 (0.58) OPRD1OPRM1CTSDOPRK1
SCHEMBL30477367 0.89 OPRM1 (0.51) KISS1ROPRD1OPRM1CTSDBACE1
SCHEMBL29804710 0.89 ACE (0.54) KISS1ROPRD1OPRM1OPRK1
SCHEMBL29405922 0.88 CTSD (0.61) OPRD1OPRM1CTSDOPRK1
SCHEMBL30493684 0.88 CTSD (0.52) CTSDBACE1BACE2
SCHEMBL31732280 0.87 OPRD1 (0.57) OPRD1OPRM1CTSDBACE1BACE2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4126921-A2 QD DOSING OF GIP RECEPTOR AGONIST PEPTIDE COMPOUNDS AND USES THEREOF Takeda Pharmaceutical Company Limited (JP) 2023-02-08 — — EP claimed
CN-115335395-A QD administration of GIP receptor agonist peptide compounds and uses thereof 武田药品工业株式会社 2022-11-11 — — CN claimed
US-20220227830-A1 QD DOSING OF GIP RECEPTOR AGONIST PEPTIDE COMPOUNDS AND USES THEREOF TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2022-07-21 — — US claimed
EP-4126921-A2 QD DOSING OF GIP RECEPTOR AGONIST PEPTIDE COMPOUNDS AND USES THEREOF Takeda Pharmaceutical Company Limited (JP) 2023-02-08 — — EP disclosed
CN-115335395-A QD administration of GIP receptor agonist peptide compounds and uses thereof 武田药品工业株式会社 2022-11-11 — — CN disclosed
US-20220227830-A1 QD DOSING OF GIP RECEPTOR AGONIST PEPTIDE COMPOUNDS AND USES THEREOF TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2022-07-21 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220227830-A1 QD DOSING OF GIP RECEPTOR AGONIST PEPTIDE COMPOUNDS AND USES THEREOF GIPR, GLP1R, GRPR KISS1R 95/4885OPRD1 253/4885OPRM1 339/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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