Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 4/20 | 0.64 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.64 |
| ▸ | LTA4H | P09960 | 3/20 | 0.62 |
| ▸ | PPARA | Q07869 | 3/20 | 0.59 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.54 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.54 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.53 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15061644 | 0.93 | HDAC1 (0.62) | HDAC1HDAC2PPARAKCNA3L3MBTL1 | |
| SCHEMBL10361085 | 0.91 | HDAC1 (0.65) | HDAC1HDAC2PPARAKCNA3L3MBTL1 | |
| SCHEMBL4055883 | 0.88 | L3MBTL1 (0.61) | HDAC1HDAC2KCNA3L3MBTL1 | |
| SCHEMBL7737575 | 0.87 | HDAC1 (0.69) | HDAC1HDAC2LTA4HPPARAFFAR1 | |
| SCHEMBL7739114 | 0.85 | HDAC1 (0.72) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL7738398 | 0.85 | HDAC1 (0.72) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL8278956 | 0.82 | MTNR1A (0.59) | HDAC1HDAC2KCNA3L3MBTL1 | |
| SCHEMBL11587499 | 0.81 | FFAR4 (0.75) | HDAC1HDAC2LTA4HPPARAFFAR1 | |
| SCHEMBL15849204 | 0.80 | TSHR (0.71) | L3MBTL1 | |
| SCHEMBL16156097 | 0.80 | TSHR (0.71) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997049668-A1 | INHIBITIORS OF CYSTEINE PROTEASE | SMITHKLINE BEECHAM CORPORATION (US) | 1997-12-31 | — | — | WO | claimed |