Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 7/20 | 0.62 |
| ▸ | HDAC2 | Q92769 | 7/20 | 0.62 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.56 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.56 |
| ▸ | PPARA | Q07869 | 2/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.54 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.54 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.54 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10361085 | 0.98 | HDAC1 (0.65) | HDAC1HDAC2KCNA3L3MBTL1MTNR1A | |
| SCHEMBL4055883 | 0.94 | L3MBTL1 (0.61) | HDAC1HDAC2KCNA3L3MBTL1MTNR1A | |
| SCHEMBL8823916 | 0.93 | HDAC1 (0.64) | HDAC1HDAC2KCNA3L3MBTL1PPARA | |
| SCHEMBL7737575 | 0.90 | HDAC1 (0.69) | HDAC1HDAC2PPARAHDAC3HDAC4 | |
| SCHEMBL8278956 | 0.88 | MTNR1A (0.59) | HDAC1HDAC2KCNA3L3MBTL1MTNR1A | |
| SCHEMBL7738398 | 0.88 | HDAC1 (0.72) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL7739114 | 0.88 | HDAC1 (0.72) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| Acetic Acid SCHEMBL29035456 | 0.85 | HDAC1 (0.58) | HDAC1HDAC2KCNA3L3MBTL1MTNR1A | |
| 2-Decanone SCHEMBL11590035 | 0.84 | ALDH1A1 (0.56) | HDAC1HDAC2 | |
| SCHEMBL1162023 | 0.84 | PPARA (0.74) | HDAC1HDAC2KCNA3PPARAHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8470861-B2 | Mitochondria-targeted antioxidant prodrugs and methods of use | UNIVERSITY OF ROCHESTER (US) | 2013-06-25 | — | — | US | disclosed |