Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28602855 | 0.98 | TSHR (0.45) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL13895238 | 0.85 | TSHR (0.40) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL4277447 | 0.83 | ALDH1A1 (0.45) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL28617590 | 0.83 | ALDH1A1 (0.42) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL13895233 | 0.82 | CYP1A2 (0.47) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL9067370 | 0.81 | MGAM (0.40) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL13895230 | 0.81 | TSHR (0.40) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL214047 | 0.81 | — | — | |
| SCHEMBL12275693 | 0.80 | TSHR (0.42) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL22689123 | 0.80 | TSHR (0.42) | TSHRALDH1A1TP53HIF1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113227087-A | Macrocyclic compounds and their use in the treatment of disease | 诺华股份有限公司 | 2021-08-06 | — | — | CN | disclosed |
| US-5653970-A | CLEANING COMPOUNDS; COSMETICS | LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) | 1997-08-05 | — | — | US | disclosed |
| US-5641480-A | ENHANCED STABILITY AND/OR VISCOSITY, CLARITY | LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) | 1997-06-24 | — | — | US | disclosed |
| US-5624906-A | Oral hygiene compositions comprising heteroatom containing alkyl aldonamide compounds | LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) | 1997-04-29 | — | — | US | disclosed |
| US-5521293-A | Heteroatom containing alkyl aldonamide compounds as superior foaming, more soluble nonionic surfactants and a process for their manufacture | LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) | 1996-05-28 | — | — | US | disclosed |