Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 5/20 | 0.45 |
| ▸ | DGKA | P23743 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.33 |
| ▸ | GABRD | O14764 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13895238 | 0.89 | TSHR (0.40) | CYP1A2TSHRDGKAALDH1A1THRB | |
| SCHEMBL3224284 | 0.89 | TSHR (0.55) | TSHRDGKAALDH1A1TP53HIF1A | |
| SCHEMBL28617590 | 0.88 | ALDH1A1 (0.42) | CYP1A2TSHRDGKAALDH1A1THRB | |
| SCHEMBL4277447 | 0.85 | ALDH1A1 (0.45) | TSHRDGKAALDH1A1THRBMAPT | |
| SCHEMBL1614567 | 0.83 | TSHR (0.61) | CYP1A2TSHRDGKAALDH1A1THRB | |
| SCHEMBL13895230 | 0.82 | TSHR (0.40) | TSHRDGKAALDH1A1THRBMAPT | |
| SCHEMBL8824261 | 0.82 | TSHR (0.42) | TSHRALDH1A1THRBMAPTTP53 | |
| SCHEMBL13325750 | 0.81 | TSHR (0.44) | TSHRDGKAALDH1A1MAPTTP53 | |
| SCHEMBL7256465 | 0.81 | ALDH1A1 (0.54) | TSHRDGKAALDH1A1MAPTTP53 | |
| SCHEMBL28975255 | 0.81 | TSHR (0.40) | CYP1A2TSHRDGKAALDH1A1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7524977-B2 | Process for producing fluoroalkanesulfonamide derivatives | CENTRAL GLASS COMPANY, LIMITED (JP) | 2009-04-28 | — | — | US | disclosed |
| US-20080058538-A1 | Process for producing fluoroalkanesulfonamide derivatives | CENTRAL GLASS COMPANY, LIMITED (JP) | 2008-03-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080058538-A1 | Process for producing fluoroalkanesulfonamide derivatives | AFF1, AFF2, RER1 | CYP1A2 346/4885TSHR 383/4885DGKA 3425/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.