SCHEMBL8824342

SCHEMBL8824342

Cc1ccc(C(C)C)c(-c2ccc(-c3cc(C)ccc3C(C)C)cc2)c1

nearest known ligand 0.54

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.54
LMNA P02545 1/20 0.54
CHRM1 P11229 1/20 0.54
SLC6A2 P23975 1/20 0.54
ADRA1A P35348 1/20 0.54
HTR2B P41595 1/20 0.54
CNR1 P21554 2/20 0.43
CNR2 P34972 2/20 0.43
MAOA P21397 1/20 0.40
MAOB P27338 1/20 0.40
ELANE P08246 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2A6 P11509 1/20 0.39
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA9 Q16790 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28000746 0.90 TRPA1 (0.55) TRPA1LMNACHRM1SLC6A2ADRA1A
SCHEMBL29239427 0.90 TRPA1 (0.48) TRPA1LMNACHRM1SLC6A2ADRA1A
SCHEMBL6668337 0.88 TRPA1 (0.60) TRPA1LMNACHRM1SLC6A2ADRA1A
SCHEMBL30320821 0.88 TRPA1 (0.60) TRPA1LMNACHRM1SLC6A2ADRA1A
SCHEMBL21725464 0.86 HRH3 (0.42) TRPA1LMNACHRM1SLC6A2ADRA1A
SCHEMBL21508397 0.83 TRPA1 (0.43) TRPA1LMNACHRM1SLC6A2ADRA1A
SCHEMBL10094399 0.82 ACHE (0.43) TRPA1LMNACHRM1SLC6A2ADRA1A
SCHEMBL21508017 0.82 ALKBH3 (0.42) TRPA1LMNACHRM1SLC6A2ADRA1A
SCHEMBL30146912 0.78 TRPA1 (0.50) TRPA1LMNACHRM1SLC6A2ADRA1A
Ammonia Solution, Strong SCHEMBL4589935 0.78 TRPA1 (0.40) TRPA1LMNACHRM1SLC6A2ADRA1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0680833-B1 Recording material for direct thermal imaging AGFA GEVAERT NV (BE) 1997-09-10 EP claimed
US-5559075-A LEUCO DYE, METAL SALT, REDUCING AGENT AGFA-GEVAERT (BE) 1996-09-24 US claimed
EP-0680833-A1 Recording material for direct thermal imaging AGFA-GEVAERT N.V. (BE) 1995-11-08 EP claimed
EP-0680833-B1 Recording material for direct thermal imaging AGFA GEVAERT NV (BE) 1997-09-10 EP disclosed
US-5559075-A LEUCO DYE, METAL SALT, REDUCING AGENT AGFA-GEVAERT (BE) 1996-09-24 US disclosed
EP-0680833-A1 Recording material for direct thermal imaging AGFA-GEVAERT N.V. (BE) 1995-11-08 EP disclosed