Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL4589935

CC(C)c1ccc2cc1-2.N

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.40
CA1 P00915 3/20 0.39
CA2 P00918 3/20 0.39
LMNA P02545 2/20 0.38
SLC6A2 P23975 2/20 0.38
HTR2B P41595 2/20 0.38
CHRM1 P11229 1/20 0.38
ADRA1A P35348 1/20 0.38
CA12 O43570 1/20 0.37
CA9 Q16790 1/20 0.37
ALOX5AP P20292 1/20 0.35
FEN1 P39748 1/20 0.35
RPS6KA3 P51812 1/20 0.34
GABRA1 P14867 2/20 0.33
GABRB2 P47870 2/20 0.33
TRPV1 Q8NER1 2/20 0.33
FAAH O00519 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
HPGD P15428 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10598465 0.80 MEN1 (0.47) CA1CA2LMNACA12CA9
Ammonia Solution, Strong SCHEMBL4603639 0.79 CA1 (0.44) TRPA1CA1CA2LMNASLC6A2
SCHEMBL8824342 0.78 TRPA1 (0.54) TRPA1CA1CA2LMNASLC6A2
SCHEMBL9813433 0.77 ANPEP (0.44) CA1CA2LMNACA12CA9
SCHEMBL9468971 0.77 ANPEP (0.44) TRPA1CA1CA2LMNASLC6A2
SCHEMBL30792432 0.77 ANPEP (0.44) CA1CA2LMNACA12CA9
SCHEMBL27519877 0.75 ESR1 (0.44) TRPA1CA1CA2LMNASLC6A2
SCHEMBL10094417 0.75 ROCK2 (0.39) CA1CA2CA12CA9RPS6KA3
SCHEMBL9876285 0.73 RXRA (0.46) TRPA1CA1CA2LMNASLC6A2
SCHEMBL21508397 0.72 TRPA1 (0.43) TRPA1LMNASLC6A2HTR2BCHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080244963-A1 Lead-Free Aviation Fuel TOTAL FRANCE (FR) 2008-10-09 US claimed
US-20080244963-A1 Lead-Free Aviation Fuel TOTAL FRANCE (FR) 2008-10-09 US disclosed