SCHEMBL4587261

SCHEMBL4587261

Cn1cncc1C[C@@H](N)C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SLC1A3 P43003 1/20 0.51
GRIA4 P48058 6/20 0.45
GRIA1 P42261 6/20 0.45
GRIA3 P42263 6/20 0.45
GRIA2 P42262 5/20 0.45
SLC7A5 Q01650 3/20 0.45
CYP3A4 P08684 1/20 0.45
NOS1 P29475 3/20 0.45
HSD17B10 Q99714 1/20 0.41
ALPI P09923 1/20 0.41
PKM P14618 1/20 0.41
PTGS1 P23219 1/20 0.41
XIAP P98170 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28560 1.00 SLC1A3 (0.51) SLC1A3GRIA4GRIA1GRIA3GRIA2
SCHEMBL8824879 1.00 SLC1A3 (0.51) SLC1A3GRIA4GRIA1GRIA3GRIA2
SCHEMBL8824882 1.00 SLC1A3 (0.51) SLC1A3GRIA4GRIA1GRIA3GRIA2
SCHEMBL28559 1.00 SLC1A3 (0.51) SLC1A3GRIA4GRIA1GRIA3GRIA2
Hydrochloric Acid SCHEMBL7049998 0.98 SLC1A3 (0.50) SLC1A3GRIA4GRIA1GRIA3GRIA2
Homoserine SCHEMBL28894150 0.91 NOS1 (0.45) SLC1A3GRIA4GRIA1GRIA3GRIA2
SCHEMBL12610414 0.91 SLC1A3 (0.44) SLC1A3GRIA4GRIA1GRIA3GRIA2
SCHEMBL12610410 0.91 SLC1A3 (0.44) SLC1A3GRIA4GRIA1GRIA3GRIA2
Sarcosine SCHEMBL16540746 0.89 SLC1A3 (0.43) SLC1A3GRIA4GRIA1GRIA3GRIA2
Sarcosine SCHEMBL16540745 0.89 SLC1A3 (0.43) SLC1A3GRIA4GRIA1GRIA3GRIA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122070294-A Stable vitreous material based on histidine, arginine and glutamic acid amino acids 阵序补丁有限公司 2026-05-19 CN disclosed
WO-2025032025-A1 STABLE GLASSY MATERIAL BASED ON HISTIDINE, ARGININE AND GLUTAMIC ACID AMINO ACIDS VITROPEP (FR) 2025-02-13 WO disclosed
US-20230391828-A1 REGULATORS OF CELL DIVISION TECHNISCHE UNIVERSITAT DRESDEN (DE) 2023-12-07 US disclosed
EP-3981784-A1 REGULATORS OF CELL DIVISION Technische Universität Dresden (DE) 2022-04-13 EP disclosed
US-8921306-B2 Nociceptin mimetics THE UNIVERSITY OF QUEENSLAND (AU) 2014-12-30 US disclosed
US-20130157928-A1 NOCICEPTIN MIMETICS THE UNIVERSITY OF QUEENSLAND (AU) 2013-06-20 US disclosed
EP-2576598-A1 NOCICEPTIN MIMETICS The University of Queensland (AU) 2013-04-10 EP disclosed
WO-2011153583-A1 NOCICEPTIN MIMETICS THE UNIVERSITY OF QUEENSLAND (AU) 2011-12-15 WO disclosed
EP-1737884-A4 ALPHA HELICAL MIMICS, THEIR USES AND METHODS FOR THEIR PRODUCTION UNIV QUEENSLAND (AU) 2008-10-29 EP disclosed
WO-2008077194-A1 RECEPTOR AGONISTS XENOME LTD (AU) 2008-07-03 WO disclosed
US-7253194-B2 Compounds and inhibitors of phospholipases THE UNIVERSITY OF QUEENSLAND (AU) 2007-08-07 US disclosed
EP-1737884-A1 ALPHA HELICAL MIMICS, THEIR USES AND METHODS FOR THEIR PRODUCTION The University of Queensland (AU) 2007-01-03 EP disclosed
EP-1402021-A4 A GENE AND USES THEREFOR AUTOGEN RES PTY LTD (AU) 2005-11-09 EP disclosed
WO-2005090388-A1 ALPHA HELICAL MIMICS, THEIR USES AND METHODS FOR THEIR PRODUCTION THE UNIVERSITY OF QUEENSLAND (AU) 2005-09-29 WO disclosed
EP-1402021-A1 A GENE AND USES THEREFOR Autogen Research Pty. Ltd. (AU) 2004-03-31 EP disclosed
US-20030216441-A1 Farnesyltransferase inhibitors WEINSTOCK, STEVEN F. 2003-11-20 US disclosed
WO-2002095020-A1 A GENE AND USES THEREFOR AUTOGEN RESEARCH PTY LTD (AU) 2002-11-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130157928-A1 NOCICEPTIN MIMETICS OPRL1, OGFRL1, OPRK1 SLC1A3 671/4885GRIA4 87/4885GRIA1 40/4885
US-20030216441-A1 Farnesyltransferase inhibitors FNTA, FNTB, LCAT SLC1A3 4388/4885GRIA4 4508/4885GRIA1 3283/4885
US-20230391828-A1 REGULATORS OF CELL DIVISION PCNA, BOD1L1, MKI67 SLC1A3 4406/4885GRIA4 4672/4885GRIA1 4073/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.