Homoserine

Homoserine

SCHEMBL28894150

Cn1cncc1CC(N)C(=O)O.NC(CCO)C(=O)O

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
NOS1 P29475 3/20 0.45
SLC1A3 P43003 1/20 0.44
GRIA4 P48058 5/20 0.40
GRIA1 P42261 5/20 0.40
GRIA3 P42263 5/20 0.40
GRIA2 P42262 4/20 0.40
SLC7A5 Q01650 2/20 0.39
CYP3A4 P08684 1/20 0.39
HSD17B10 Q99714 1/20 0.36
ARG1 P05089 1/20 0.35
ALPI P09923 1/20 0.35
PKM P14618 1/20 0.35
PTGS1 P23219 1/20 0.35
XIAP P98170 1/20 0.35
GRIK1 P39086 1/20 0.34
GRIK2 Q13002 1/20 0.34
GRIK3 Q13003 1/20 0.34
GRIK4 Q16099 1/20 0.34
GRIK5 Q16478 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8824882 0.91 SLC1A3 (0.51) NOS1SLC1A3GRIA4GRIA1GRIA3
SCHEMBL28559 0.91 SLC1A3 (0.51) NOS1SLC1A3GRIA4GRIA1GRIA3
SCHEMBL28560 0.91 SLC1A3 (0.51) NOS1SLC1A3GRIA4GRIA1GRIA3
SCHEMBL8824879 0.91 SLC1A3 (0.51) NOS1SLC1A3GRIA4GRIA1GRIA3
SCHEMBL4587261 0.91 SLC1A3 (0.51) NOS1SLC1A3GRIA4GRIA1GRIA3
Hydrochloric Acid SCHEMBL7049998 0.90 SLC1A3 (0.50) NOS1SLC1A3GRIA4GRIA1GRIA3
Racemethionine SCHEMBL27710848 0.85 NOS1 (0.43) NOS1SLC1A3GRIA4GRIA1GRIA3
Lysine SCHEMBL28097203 0.85 GSR (0.51) NOS1SLC1A3GRIA4GRIA1GRIA3
SCHEMBL27203721 0.84 NOS1 (0.42) NOS1SLC1A3GRIA4GRIA1GRIA3
SCHEMBL12610414 0.83 SLC1A3 (0.44) NOS1SLC1A3GRIA4GRIA1GRIA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115389756-B Detection kit for predicting risk of atrial fibrillation and application thereof 首都医科大学附属北京安贞医院 2023-02-17 CN disclosed
CN-115389756-A Detection kit for predicting risk of atrial fibrillation and application thereof 首都医科大学附属北京安贞医院 2022-11-25 CN disclosed