Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.49 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | GFER | P55789 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9176305 | 0.93 | CYP4F2 (0.47) | CYP4F2CYP4A11ALDH1A1GFERGAA | |
| SCHEMBL8825405 | 0.88 | HPGD (0.50) | CYP4F2CYP4A11ALDH1A1GAAKDM4E | |
| SCHEMBL8825474 | 0.81 | KDM4E (0.45) | ALDH1A1KDM4EHPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL19065281 | 0.79 | ALDH1A1 (0.46) | CYP4F2CYP4A11ALDH1A1GFERGAA | |
| SCHEMBL8825186 | 0.78 | ALDH1A1 (0.44) | CYP4F2CYP4A11ALDH1A1GFERGAA | |
| SCHEMBL8825306 | 0.74 | KDM4E (0.48) | ALDH1A1GFERGAAKDM4EHPGD | |
| SCHEMBL9176562 | 0.72 | FFAR1 (0.51) | ALDH1A1GFERGAA | |
| SCHEMBL8825252 | 0.71 | KDM4E (0.46) | ALDH1A1GFERGAAKDM4EHPGD | |
| SCHEMBL11243916 | 0.71 | CYP4F2 (0.58) | CYP4F2CYP4A11ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL22922181 | 0.70 | CYP4F2 (0.59) | CYP4F2CYP4A11ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5624943-A | Pyridine compounds which are useful as leukotriene-B4 -antagonists | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-04-29 | — | — | US | disclosed |