Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | AR | P10275 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.45 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.45 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8825286 | 0.87 | ALDH1A1 (0.61) | RAB9AMAPTNPC1ALDH1A1KMT2A | |
| SCHEMBL8341931 | 0.82 | TARBP2 (0.60) | RAB9AMAPTLMNANPC1ALDH1A1 | |
| SCHEMBL8825390 | 0.82 | ALDH1A1 (0.53) | RAB9AGAAHTTL3MBTL1MAPT | |
| SCHEMBL893056 | 0.81 | HDAC1 (0.57) | RAB9AGAAMAPTLMNANPC1 | |
| SCHEMBL8825172 | 0.81 | ALDH1A1 (0.75) | RAB9AGAAHTTL3MBTL1MAPT | |
| SCHEMBL8825404 | 0.81 | ALDH1A1 (0.52) | RAB9AHTTMAPTNPC1ALDH1A1 | |
| SCHEMBL8825348 | 0.81 | L3MBTL1 (0.58) | RAB9AGAAHTTL3MBTL1MAPT | |
| SCHEMBL8825537 | 0.80 | CDC7 (0.51) | RAB9AGAAMAPTLMNANPC1 | |
| SCHEMBL8825115 | 0.80 | ALDH1A1 (0.51) | HTTMAPTLMNAALDH1A1KMT2A | |
| SCHEMBL8825164 | 0.79 | HTT (0.50) | RAB9AGAAHTTL3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5622976-A | NERVOUS SYSTEM DISORDERS; ALZHEIMER*S DISEASE; CEREBROVASCULAR DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-04-22 | — | — | US | disclosed |
| EP-0619814-A1 | OXADIAZOLE DERIVATIVES HAVING ACETYLCHOLINESTERASE-INHIBITORY AND MUSCARINIC AGONIST ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-19 | — | — | EP | disclosed |
| WO-1993013083-A1 | OXADIAZOLE DERIVATIVES HAVING ACETYLCHOLINESTERASE-INHIBITORY AND MUSCARINIC AGONIST ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-08 | — | — | WO | disclosed |